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ITFG2 Mouse anti-Human, Clone: OTI 2H5, lyophilized, TrueMAB™
Mouse Monoclonal Antibody
Marca: Origene Technologies CF503044
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Descripción
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
As part of the KICSTOR complex functions in the amino acid-sensing branch of the TORC1 signaling pathway. Recruits, in an amino acid-independent manner, the GATOR1 complex to the lysosomal membranes and allows its interaction with GATOR2 and the RAG GTPases. Functions upstream of the RAG GTPases and is required to negatively regulate mTORC1 signaling in absence of amino acids. In absence of the KICSTOR complex mTORC1 is constitutively localized to the lysosome and activated. The KICSTOR complex is also probably involved in the regulation of mTORC1 by glucose.Especificaciones
ITFG2 | |
Monoclonal | |
Unconjugated | |
ITFG2 | |
FGGAP1, MDS028 | |
Mouse | |
Affinity Chromatography | |
RUO | |
55846 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot | |
OTI 2H5 | |
PBS with 8% trehalose and no preservative; pH 7.3 | |
Q969R8 | |
ITFG2 | |
Full length human recombit protein of human ITFG2 produced in HEK293T cell. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG1 |
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Título del producto
ITFG2 Mouse anti-Human, Clone: OTI 2H5, lyophilized, TrueMAB™
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