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  6. 30001470

Jasplakinolide, Tocris Bioscience™

Catalog Number 30001470
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Cantidad:
100 μg
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Descripción

Stabilizes F-actin; promotes actin polymerization

Rapidly stabilizes pre-formed actin filaments and inhibits their disassembly in vitro. Also induces polymerization of actin monomers into F-actin in vivo. Shown to bind to F-actin competitively with phalloidin (Cat. No. 4535) (Kd ∽ 15 nM). Exhibits antifungal and antiproliferative effects (IC50 = 35 nM for antiproliferative activity in PC3 cells). Cell permeable.
Nombre del producto químico o material Jasplakinolide
CAS 102396-24-7
Fórmula molecular C36H45BrN4O6
Cantidad 100 μg
Sinónimo jasplakinolide
Clave InChI GQWYWHOHRVVHAP-JFKHFEEVSA-N
SMILES CC1CC(OC(=O)CC(NC(=O)C(N(C(=O)C(NC(=O)C(CC(=C1)C)C)C)C)CC2=C(NC3=CC=CC=C32)Br)C4=CC=C(C=C4)O)C
Nombre IUPAC (4R,7R,10S,13S,15E,17R,19R)-7-[(2-bromo-1H-indol-3-yl)methyl]-4-(4-hydroxyphenyl)-8,10,13,15,17,19-hexamethyl-1-oxa-5,8,11-triazacyclononadec-15-ene-2,6,9,12-tetrone
Peso molecular (g/mol) 709.682
PubChem CID 131843168
Formula Weight (peso de la fórmula) 709.67
Porcentaje de pureza >97%
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