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KappaB ras2 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marca: Invitrogen PA529432
Detalles adicionales : Peso : 0.01000kg
Descripción
Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji. Predicted reactivity: Mouse (100%), Rat (100%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.Especificaciones
| KappaB ras2 | |
| Polyclonal | |
| Unconjugated | |
| NKIRAS2 | |
| 2410003M04Rik; 4930527H08Rik; D630018G21Rik; I-kappa-B-interacting Ras-like protein 2; Kappa B-Ras protein 2; kappaB-Ras2; KBRAS2; NF-kappa-B inhibitor-interacting Ras-like protein 2; NFKB inhibitor interacting Ras like 2; NFKB inhibitor interacting Ras-like 2; NFKB inhibitor interacting Ras-like protein 2; NKIRAS2 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 28511 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunocytochemistry, Western Blot | |
| 1 mg/mL | |
| 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7 | |
| Q9NYR9 | |
| NKIRAS2 | |
| Synthetic peptide corresponding to a region within amino acids 129 and 191 of Human NKIRAS2 | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |