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CD117/c-Kit/SCF-Receptor Ab-3 Mouse Monoclonal Antibody, Epredia™
Obtain accurate, reproducible results in immunohistochemistry and immunofluorescence experiments.
Marca: Epredia MS-289-P1ABX
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Descripción
c-kit is a transmembrane receptor tyrosine kinase. It binds to stem cell factor (SCF). It is expressed in many tissues and cells. C-kit/SCf is involved in development of several lineages of stem cells, such as germ cells, neural crest-derived melanocytes and hematopoietic precursor cells. Ab-3 does not interfere with the binding of SCF to c-kitHost Species: Mouse
Clone: K45
Isotype: IgG2a
Species Reactivity: Human. Others not known.
Epitope: Extracellular second N-terminus Ig-like domain of c-kit
Immunogen: Recombinant human extracellular c-kit fragment
Molecular Weight: 145kDa
Positive Control: Skin, GI Stromal Tumor (GIST)
Cellular Localization: Membrane/cytoplasmic
Recommended for:
- Immunohistochemistry (Frozen or fixed in methacarn or Stieve's and embedded in paraffin)
- Immunofluorescence
Note:
USA: RUO; Int'l: RUO
Especificaciones
| CD117/c-Kit/SCF-Receptor Ab-3 | |
| Monoclonal | |
| 1mg/mL | |
| Mouse | |
| 100 μL | |
| Primary | |
| Concentrated |
| Immunofluorescence, Immunohistochemistry (Frozen) | |
| K45 | |
| Unconjugated | |
| Recombinant human extracellular c-kit fragment | |
| RUO | |
| Human | |
| IgG2a |