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Invitrogen™ LRRK2 (WT) Recombinant Protein
Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene, which codes for a multi-domain protein kinase, are considered the most common genetic cause of late-onset autosomal-dominant Parkinson's disease.
Marca: Invitrogen™ A15198
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Descripción
This full-length, purified and active wild-type LRRK2 protein may be useful in research to better understand the native protein, unaffected by mutations, as well as to explore the mechanisms underlying Parkinson's disease.
- Increase disease relevance by interrogating a purified and active full-length LRRK2 protein
- Uncover novel compounds or hits specific to the full-length form
- Advance Parkinson's research using the full-length protein and validated assays
Especificaciones
| NP_940980.3 | |
| 120892 | |
| 100μg | |
| LRRK Kinase Family | |
| DYKDDDDK | |
| Baculovirus | |
| Recombinant, Full Length | |
| Neurobiology |
| Kinase Assay | |
| 288 kDa | |
| AURA17, DARDARIN, PARK8, RIPK7, ROCO2 | |
| Human | |
| Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws. If properly stored, this product is guaranteed for 6 months from date of purchase. | |
| Kinases & Inhibitors | |
| Liquid |