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Cytiva™ MabSelect™ VL Protein L Resin
The MabSelect™ VL resin is a protein L resin for affinity capture of antibody Fabs, bispecifics, and other variants containing a kappa light chain.
Marca: Cytiva™ 17542001
Descripción
MabSelect™ VL resin with a redesigned protein L ligand for high binding capacity and improved alkaline stability. For affinity capture of antibody Fabs, bispecifics, and other variants containing a kappa light chain.
- High dynamic binding capacity protein L resin for efficient capture of antibody Fabs, bispecifics, and variants containing a kappa light chain
- Stable when cleaned with 0.1 M NaOH, reducing risk for bioburden incidents
- Provides good resolution for product-related impurities in the capture of bispecific antibodies
As the diversity of antibody variants increases, so does the need for chromatography resins that can capture and purify these variants. As an alternative to protein A, protein L resin can be used to capture antibody Fabs, bispecific antibodies, and other molecules containing kappa variants of the variable light (VL) chain. Protein L binds human kappa light chain subtypes 1, 3, and 4 and mouse kappa light chain subtype 1.

Especificaciones
25 mL | |
Alkaline Stabilized Protein L-derived (E. coli) | |
60 μm | |
Cromatografía de afinidad de anticuerpos |
300 cm/hr. | |
De 2 a 10 | |
2°C to 8°C, 20% Ethanol | |
VL Protein L Resin |
Seguridad y manipulación
- MabSelect VL, 25 ml
Palabra de advertencia
- Atención
Clasificación
- Líquido inflamable Categoría 3
Indicaciones de peligro
- H226-Líquidos y vapores inflamables.
Consejos de prudencia
- P210-Mantener alejado del calor, de superficies calientes, de chispas, de llamas abiertas y de cualquier otra fuente de ignición. No fumar.
- P501b-Eliminar el contenido/el recipiente en conforme a la reglamentación local/regional/nacional/internacional.
Otros peligros
- MIXTURE LIST-Contém: ethanol
- UNKNOWN ACUTE-16.5% de la mezcla consiste en uno o varios componentes de toxicidad aguda desconocida.
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