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Metformin hydrochloride, Tocris Bioscience™

Catalog Number 30001457
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Cantidad:
100 mg
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Descripción

Activator of LKB1/AMPK; antidiabetic agent

Metformin hydrochloride is an antidiabetic agent; lowers plasma glucose levels and improves insulin sensitivity. Inhibits hepatic gluconeogenesis via activation of the LKB1/AMPK pathway. Displays antiproliferative effects in cancer cell lines via inhibition of mitochondrial complex I (MRC-1). Activates the aPKC-CBP pathway in neural precursors to promote neurogenesis. Activates autophagy. Identified by chemoinformatics as targeting human host proteins that interact with SARS-CoV-2.
Nombre del producto químico o material Metformin hydrochloride
CAS 1115-70-4
Fórmula molecular C4H12ClN5
Número MDL MFCD00012582
Cantidad 100 mg
Sinónimo metformin hydrochloride, 1,1-dimethylbiguanide hydrochloride, metformin hcl, glucophage, riomet, diabefagos, meguan, metformin monohydrochloride, benofomin, denkaform
Clave InChI OETHQSJEHLVLGH-UHFFFAOYSA-N
SMILES [H+].[Cl-].CN(C)C(=N)N=C(N)N
Nombre IUPAC hydrogen 1-[(diaminomethylidene)amino]-N,N-dimethylmethanimidamide chloride
Peso molecular (g/mol) 165.63
PubChem CID 14219
Formula Weight (peso de la fórmula) 165.62
Porcentaje de pureza >98%
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