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Tocris Bioscience™ MK 886
Inhibitor of 5-lipoxygenase-activating protein (FLAP)
Marca: Tocris Bioscience™ 1311/2
Detalles adicionales : Peso : 0.00970kg
Descripción
MK 886 is a potent inhibitor of 5-lipoxygenase-activating protein (FLAP) (IC50 = 30 nM for inhibition of [125I]-L-691,678 photoaffinity labelling). Inhibits leukotriene biosynthesis (IC50 = 3 nM in human polymorphonuclear leukocytes). Also moderately potent PPARα antagonist (IC50 = 0.5-1 μM). Orally active in vivo.Especificaciones
| 1-[(4-Chlorophenyl)methyl]-3-[(1,1-dimethylethyl)thio]-α,α-dimethyl-5-(1-methylethyl)-1H-Indole-2-propanoic acid | |
| 2 mg | |
| C27H34ClNO2S |
| 118414-82-7 | |
| Lipoxygenase Inhibitors | |
| 98% |