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Tocris Bioscience™ MK6-83
TRPML channel activator
Marca: Tocris Bioscience™ 5547/10
Detalles adicionales : CAS : 1062271-24-2 Peso : 0.00970kg
Descripción
MK6-83 is a TRPML channel activator (EC50 = 110 nM). Also activates F408Δ and F465L TRPML mutants (EC50 values are 0.1 and 1.23 μM respectively). Restores endolysosomal trafficking and zinc homeostasis in lysosomes of mucolipidosis type IV (MLIV) mutant fibroblasts.Especificaciones
MK6-83 | |
5-Methyl-N-[2-(1-piperidinyl)phenyl]-2-thiophenesulfonamide | |
Soluble to 100mM in DMSO and to 20mM in ethanol | |
Bioactive Small Molecule |
1062271-24-2 | |
10 mg | |
Solid |
Research Use Only. Not For Human or Veterinary Use