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ACROBiosystems Mouse OX40 Ligand / TNFSF4 Protein, Fc Tag
350.80€ - 2419.31€
Especificaciones
Peso molecular | 43.8 kDa |
---|---|
Fuente | Mouse O x 40 Ligand, Fc Tag (OXL-M526x) is expressed from human 293 cells (HEK293). It contains AA Gln 49 - Leu 198 (Accession # P43488). |
Inmunógeno | Gln 49 - Leu 198 |
Requisitos de almacenamiento | -20°C |
Alias de gen | OX40L,TNFSF4,CD252,Glycoprotein Gp34,TXGP1,CD134 ligand,CD134L |
Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
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Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
15807427
|
ACROBiosystems
OXL-M526X-1MG |
1 mg |
2419.31€
1 miligramo |
Fecha estimada de envío: 07-08-2024 Inicie sesión para ver el stock |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | ||||
15897417
|
ACROBiosystems
OXL-M526X-100UG |
100 μg |
350.80€
100 microgramos |
Fecha estimada de envío: 07-08-2024 Inicie sesión para ver el stock |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | ||||
Descripción
Tumor necrosis factor ligand superfamily member 4 (TNFSF4) is also known as glycoprotein Gp34, OX40 ligand (OX40L), TAX transcriptionally-activated glycoprotein 1 and CD252, which belongs to the tumor necrosis factor family. TNFSF4 is the ligand for CD134 and is expressed on such cells as DC2s (a subtype of dendritic cells) enabling amplification of Th2 cell differentiation. The interaction of TNFSF4-TNFSF4 is involved in the pathogenesis of multiple autoimmune and inflammatory diseases such as systemic lupus erythematosus (SLE), carotid artery disease and cancer. Furthermore, similar to other TNF superfamily members, membrane-bound OX40 Ligand (TNFSF4) exists as a homotrimer. Human TNFSF4 shares 46% amino acid sequence identity with its mouse counterpart.
This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 43.8 kDa. The protein migrates as 47-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Especificaciones
43.8 kDa | |
Gln 49 - Leu 198 | |
OX40L,TNFSF4,CD252,Glycoprotein Gp34,TXGP1,CD134 ligand,CD134L | |
Unconjugated | |
Fc Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |
Mouse O x 40 Ligand, Fc Tag (OXL-M526x) is expressed from human 293 cells (HEK293). It contains AA Gln 49 - Leu 198 (Accession # P43488). | |
-20°C | |
OX40 Ligand | |
Mouse | |
Tris with Glycine, Arginine and NaCl, pH7.5 | |
HEK293 | |
Immune Checkpoint Proteins |