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P62/SQSTM1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marca: Proteintech 18420-1-AP-150UL
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Descripción
The molecular weight of p62 is predicted to be 48/ 38 kDa (depending on the isoform), while western blot analyses using this antibody detects the bands around 45-48 kDa and 60-62 kDa, respectively.
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.Especificaciones
| P62/SQSTM1 | |
| Polyclonal | |
| Unconjugated | |
| SQSTM1 | |
| P62, sequestosome 1, SQSTM1, Ubiquitin binding protein p62 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 113894, 18412, 8878 | |
| -20°C | |
| Liquid |
| Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation | |
| 0.29 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| O08623, Q13501, Q64337 | |
| Sqstm1 | |
| P62/SQSTM1 Fusion Protein Ag13131 | |
| 150 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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