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Paxillin Monoclonal Antibody (5H11), Invitrogen™
Mouse Monoclonal Antibody
Marca: Invitrogen MA513356
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Descripción
MA5-13356 targets Paxillin in IF, IHC (P), IP, and WB applications and shows reactivity with Human and Rat samples. The MA5-13356 immunogen is purified recombit full-length human paxillin protein.
Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. Paxillin associates tightly with FAK and Crk through its SH2 domain. This interaction is independent of the extracellular matrix. Although paxillin was initially discovered in fibroblasts, its phosphorylation may also be important during neurite extension during differentiation.
Especificaciones
| Paxillin | |
| Monoclonal | |
| 0.2 mg/mL | |
| PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4 | |
| P49023, Q8VI36, Q66H76 | |
| Mouse | |
| Protein G | |
| RUO | |
| 19303, 360820, 5829 | |
| 4° C | |
| Liquid |
| Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| 5H11 | |
| Unconjugated | |
| PXN | |
| PXN | |
| Purified recombit full-length human paxillin protein | |
| 500 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG1 κ |