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PDI Monoclonal Antibody (12), Invitrogen™
Mouse Monoclonal Antibody
235.00€ - 410.00€
Especificaciones
Antígeno | PDI |
---|---|
Clon | 12 |
Concentración | 1 mg/mL |
Aplicaciones | ELISA |
Clasificación | Monoclonal |
Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
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Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
17779743
|
Invitrogen
MA543389 |
50 μL |
235.00€
50 microlitros |
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17799553
|
Invitrogen
MA543004 |
100 μL |
410.00€
100 microlitros |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | |||||
Descripción
Specificity: Human P4HB
Protein disulfide isomerase (PDI) is a multifunctional protein that catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, the protein seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. It may therefore cause structural modifications of exofacial proteins. Inside the cell, PDI seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, it functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, it facilitates aggregation (anti-chaperone activity). PDI may be involved with other chaperones in the structural modification of the TG precursor in hormone biogenesis. It also acts a structural subunit of various enzymes such as prolyl 4-hydroxylase and microsomal triacylglycerol transfer protein MTTP. Receptor for LGALS9; the interaction retains P4HB at the cell surface of Th2 T helper cells, increasing disulfide reductase activity at the plasma membrane, altering the plasma membrane redox state and enhancing cell migration.Especificaciones
PDI | |
1 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
PBS with no preservative | |
1810041F13Rik; AI661267; CaO19.12595; cellular thyroid hormone binding protein; cellular thyroid hormone-binding protein; CLCRP1; collagen prolyl 4-hydroxylase beta; DSI; Endoplasmic reticulum resident protein 59; Eps1p; ER protein 59; ERBA2L; ERp59; GIT; glutathione-insulin transhydrogenase; I79_002399; LOW QUALITY PROTEIN: protein disulfide-isomerase A2; MFP1; P4HB; p4hb.L; P4Hbeta; p55; p58; Pancreas-specific protein disulfide isomerase; pancreatic protein disulfide isomerase; PDA2; PDI; PDI (E.C.5.3.4.1); PDI1; PDI1P; Pdia1; pdia2; pdia2.L; PDIP; Pdipl; PDIR; PHDB; PO4DB; PO4HB; procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide; PROHB; prolyl 4-hydroxylase beta polypeptide; Prolyl 4-hydroxylase subunit beta; prolyl 4-hydroxylase subunit beta L homeolog; prolyl 4-hydroxylase subunit beta L homeolog; prolyl 4-hydroxylase, beta polypeptide L homeolog; prolyl 4-hydroxylase, beta polypeptide; prolyl 4-hydroxylase, beta subunit; protein disulfide | |
P4hb | |
IgG1 | |
Protein A | |
Antibody |
12 | |
ELISA | |
Unconjugated | |
Mouse | |
Human | |
P07237 | |
5034 | |
Recombinant Human P4HB Protein. | |
Primary | |
-20° C, Avoid Freeze/Thaw Cycles | |
P4hb |