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Phospho-AKT1 (Ser129) Recombinant Rabbit Monoclonal Antibody (ARC1525), Invitrogen™
Rabbit Recombinant Monoclonal Antibody
Marca: Invitrogen MA535841
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Descripción
Immunogen sequence: DNSGA
AKT1 (PKB alpha) is a serine/threonine kinase that regulates cell survival. The activated enzyme inhibits apoptosis and stimulates cell cycle progression by phosphorylating numerous targets in various cell types, including cancer cells. This protein kinase is activated by insulin, PI3K, IGF1 and various other growth and survival factors. Akt promotes cell survival by inhibiting apoptosis through phosphorylation and inactivation of several targets, including forkhead transcription factors, and caspase-9. The AKT pathway is a major target for cancer drug discovery.
Especificaciones
| Phospho-AKT1 (Ser129) | |
| Monoclonal | |
| 1.16 mg/mL | |
| PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P31749 | |
| AKT1 | |
| A synthetic phosphorylated peptide around S129 of human Akt1 (P31749) | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
| Western Blot | |
| ARC1525 | |
| Unconjugated | |
| AKT1 | |
| Akt; Akt kinase; AKT serine/threonine kinase 1; Akt/PKB; akt1; AKT1 kinase; AKT1m; Akt1m protein; Akt1-PA; Akt1-PB; Akt1-PC; Akt1-PD; Akt1-PE; CAKT; C-AKT; CG4006; CG4006-PA; CG4006-PB; CG4006-PC; CG4006-PD; CG4006-PE; CWS6; dAkt; D-Akt; dAkt kinase; dAKT/dPKB; dAkt/PKB; DAKT1; DAKT1/PKB; Dmel\CG4006; Dmel_CG4006; dPKB; DRAC-PK; DRAC-PK66; DRAC-PK85; l(3)04226; l(3)89Bq; murine thymoma viral (v-akt) oncogene homolog 1; pAkt; P-AKT; PKB; PKB alpha; PKB beta; PKB gamma; PKB/AKT; PKB/dAKT; PKBalpha; PKB-ALPHA; PKBG; PRKBA; protein kinase B; Protein kinase B alpha; protein kinase B-alpha; proto-oncogene c-Akt; RAC; rac protein kinase alpha; RAC protein kinase alpha RAC-PK alpha; RAC serine/threonine protein kinase; RAC serine/threonine-protein kinase; RAC-ALPHA; RAC-alpha serine/threonine-protein kinase; RacPK; RAC-PK-alpha; RAC-PK-beta; RAC-PK-gamma; related to A and C kinases; related to PKA to PKC protein kinases; related to the A and C kinases; SD10374p; serine/threonine protein kinase | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 207 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |