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Phospho-mTOR (Ser2448) Recombinant Rabbit Monoclonal Antibody (ARC0094), Invitrogen™
Rabbit Recombinant Monoclonal Antibody
Marca: Invitrogen MA535832
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Descripción
Immunogen sequence: TDSYS
FRAP1 (mTOR) is a serine/threonine kinase that plays a critical role in cellular growth and proliferation. Perturbations in the mTOR/PI3-kinase/AKT pathway are associated with numerous forms of cancer. FRAP1 is also the target of rapamycin and its analogues, which are currently used as immunosuppressants and cancer therapeutics. Mutations affecting the gene results in Smith-Kingsmore syndrome.
Especificaciones
| Phospho-mTOR (Ser2448) | |
| Monoclonal | |
| 0.22 mg/mL | |
| PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P42345, P42346, Q9JLN9 | |
| MTOR | |
| A synthetic phosphorylated peptide around S2448 of human mTOR (P42345) | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
| Western Blot | |
| ARC0094 | |
| Unconjugated | |
| MTOR | |
| 2610315D21Rik; AI327068; angiopoietin-like factor CDT6; FK506 binding protein 12-rapamycin associated protein 1; FK506 binding protein 12-rapamycin associated protein 2; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; FKBP12-rapamycin complex-associated protein 1; FKBP-rapamycin associated protein; FKBP-rapamycin associated protein (FRAP); FKBP-rapamycin-associated protein FRAP; flat; FRAP; FRAP1; FRAP2; Mammalian target of rapamycin; mechanistic target of rapamycin; mechanistic target of rapamycin (serine/threonine kinase); mechanistic target of rapamycin kinase; Mtor; m-TOR; mTORC1; Raft1; Rapamycin and FKBP12 target 1; rapamycin and FKBP12 target-1 protein; rapamycin associated protein FRAP2; rapamycin target protein 1; RAPT1; serine/threonine-protein kinase mTOR; SKS | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 2475, 56717, 56718 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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