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pro-Brain Natriuretic Peptide Monoclonal Antibody (15F11), Invitrogen™
Mouse Monoclonal Antibody
Marca: Invitrogen MA120626
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Descripción
MA1-20626 detects proBNP in human samples.
In cardiac tissue brain natriuretic peptide (BNP) is synthesized as 134 amino acid precursor (prepro-BNP), which is cleaved by proteases to form a 26 aa "e;signal"e; peptide and a 108 aa pro-BNP. Proteolytic digestion of pro-BNP results in formation of 76 aa amino-terminal NT-proBNP and biologically active 32 aa BNP hormone molecule. Both proBNP and NTproBNP circulate in human plasma and have been proposed as markers for early diagnosis of left ventricular dysfunction as well as prognostic markers of possible cardiac complications at patients with heart failure.
Especificaciones
| pro-Brain Natriuretic Peptide | |
| Monoclonal | |
| 5.8 mg/mL | |
| PBS with 0.09% sodium azide; pH 7.4 | |
| P16860 | |
| NPPB | |
| Synthetic peptide corresponding to residues E(13) T S G L Q E Q R N H L Q G K(27) of human proBNP. | |
| 200 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG2b |
| ELISA, Western Blot | |
| 15F11 | |
| Unconjugated | |
| NPPB | |
| 5 kDa cardiac natriuretic peptide; AA408272; BNF; BNP; BNP(1-28); BNP(1-29); BNP(1-30); BNP(1-32); BNP(2-31); BNP(3-29); BNP(3-30); BNP(3-32); BNP(4-27); BNP(4-29); BNP(4-30); BNP(4-31); BNP(4-32); BNP(5-29); BNP(5-31); BNP(5-32); BNP32; BNP-34; Brain natriuretic factor; brain natriuretic peptide; Brain natriuretic peptide 32; Brain natriuretic peptide 45; brain type natriuretic peptide; gamma-brain natriuretic peptide; Iso-ANP; natriuretic peptide B; natriuretic peptide precursor B; natriuretic peptide precursor type B; natriuretic peptide type B; natriuretic peptides B; natriuretic protein; Nppb; NTproBNP; type-B natriuretic factor | |
| Mouse | |
| Protein A | |
| RUO | |
| 4879 | |
| 4° C, do not freeze | |
| Liquid |