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R&D Systems™ Mca-PLGL-Dpa-AR-NH2 Fluorogenic MMP Substrate
Applications: Bioactivity, Binding Activity
Marca: R&D Systems™ ES001
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Descripción
- Substrate for MMP-1, MMP-2, MMP-7, MMP-8, MMP-9, MMP-12, MMP-13, MMP-14, MMP-15, MMP-16, Cathepsin D, and Cathepsin E
- Contains a highly fluorescent 7-methoxycoumarin group that is efficiently quenched by resonance energy transfer to the 2, 4-dinitrophenyl group
- It can be used to measure the activities of peptidases that are capable of cleaving an amide bond between the fluorescent group and the quencher group, causing an increase in fluorescence
- Also an excellent substrate for active Cathepsins D and E
- Purity 98±1% based on HPLC
Especificaciones
| Liquid | |
| Supplied as a stock solution in dimethyl sulfoxide (DMSO) at a concentration of 7.99mg/mL or 6.07 mM. | |
| Source: Synthetic |
| Bioactivity, Binding Activity | |
| Predicted MW: 1093 Da | |
| Samples are stable for up to twelve months from date of receipt at -20° C to -70° C. The substrate can be aliquoted and stored -20° C to -70° C in a manual defrost freezer for six months. Avoid repeated freeze-thaw cycles. Protect from exposure to direct light. |
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