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Gibco™ Rat IL-2 Recombinant Protein, PeproTech®

Código de producto. 17892423
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Cantidad:
100 μg
1 mg
20 μg
250 μg
500 μg
50 μg
5 μg
Tamaño de la unidad:
1 miligramo
100 microgramos
20 microgramos
250 microgramos
5 microgramos
50 microgramos
500 microgramos
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Código de producto. 17892423

Marca: Gibco™ 4000250UG

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Description

Recombinant Protein

Recombinant Rat IL-2 is a 15.3 kDa protein containing 134 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.
TRUSTED_SUSTAINABILITY

Specifications

Número de acceso P17108
Para utilizar con (aplicación) ELISA, Functional Assay, Western Blot
Formulación protein with no preservative
ID de gen (Entrez) 116562
Peso molecular 15.3 kDa
Nombre Rat IL-2
Cantidad 50 μg
Fuente E. coli
Estado normativo RUO
Concentración de endotoxinas <1 EU/ μg
Alias de gen aldesleukin; cytokine; H-IL-2; il 2; Il2; Il-2; ILN; Interleukin; interleukin 2; interleukin 2 precursor; interleukin 2 variant IL2delta2; Interleukin2; Interleukin-2; interleukin-2 precursor; interleukin-2 precursor protein; interleukin-2; interleukin 2; Involved in regulation of T cell clonal expansion; involved in regulation of T-cell clonal expansion; lymphokine; M-IL-2; patial sequence of Interleukin-2; POIL2; porcine Interleukin 2; T cell growth factor; T-cell growth factor; T-cell growth factor (TCGF); TCGF
Nombre común IL-2
Símbolo de gen IL2
Actividad biológica The ED50 as determined by the dose-dependent stimulation of the proliferation of murine CTLL-2 cells is ≤ 0.4 ng/ml, corresponding to a specific activity of ≥ 2.5 x 10^6 units/mg
Conjugado Unconjugated
Recombinante Recombinant
Secuencia MAPTSSPAKE TQQHLEQLLL DLQVLLRGID NYKNLKLPMM LTFKFYLPKQ ATELKHLQCL ENELGALQRV LDLTQSKSFH LEDAGNFISN IRVTVVKLKG SENKFECQFD DEPATVVEFL RRWIAIAQSI ISTM
Contenido y almacenamiento -20°C
Sistema de expresión E. coli
Formulario Lyophilized
Grado de pureza o calidad ≥ 98% by SDS-PAGE gel and HPLC analyses.
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