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RbAp46/RbAp48 Monoclonal Antibody (15G12), Invitrogen™
Mouse Monoclonal Antibody
Marca: Invitrogen MA123277
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Descripción
Recommended positive controls: K562, THP-1, HL-60. Predicted molecular weight is 47.6kDa. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
RbAp48-15G12 recognizes full length RbAp48 (48 kDa) and RbAp46 (46 kDa), related nuclear proteins first isolated by their ability to interact with the carboxyl-terminus of the retinoblastoma protein (Rb). These two proteins are highly homologous at the amino acid level and are related functionally to members of the WD (Trp-Asp) repeat family of proteins. RbAp48 is one of the three subunits of CAF-1, can bind to histone H4 and is a subunit of human histone deacetylase HD1. Both RbAp48 and RbAp46 interact with HDAC1 and mSin3 in vivo.
Especificaciones
| RbAp46/RbAp48 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 20% glycerol and no preservative; pH 7 | |
| Q09028, Q16576, Q60972, Q60973 | |
| RBBP4, RBBP7 | |
| The complete coding region (amino acids 1-425) of RbAp48 expressed in E. coli. | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG2a |
| Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| 15G12 | |
| Unconjugated | |
| RBBP4 | |
| AA409861; AI173248; AU019541; BB114024; CAF-1 p48 subunit; CAF-1 subunit C; CAF-I 48 kDa subunit; CAF-I p48; chromatin assembly factor 1 subunit C; Chromatin assembly factor I p48 subunit; chromatin assembly factor/CAF-1 p48 subunit; G1/S transition control protein-binding protein; G1/S transition control protein-binding protein RbAp46; histone acetyltransferase type B subunit 2; Histone-binding protein RBBP4; histone-binding protein RBBP7; lin-53; mRbAp46; mRbAp48; MSI1 protein homolog; nucleosome-remodeling factor subunit RBAP46; Nucleosome-remodeling factor subunit RBAP48; NURF55; RB binding protein 4, chromatin remodeling factor; RB binding protein 7, chromatin remodeling factor; Rbap46; RBAP48; Rbbp4; RBBP-4; RBBP7; RBBP-7; retinoblastoma binding protein 4; retinoblastoma binding protein 7; retinoblastoma-binding protein 4; Retinoblastoma-binding protein 7; retinoblastoma-binding protein p46; Retinoblastoma-binding protein p48; retinoblastoma-binding protein RbAp46 | |
| Mouse | |
| Protein G | |
| RUO | |
| 19646, 245688, 5928, 5931 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |