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R&D Systems™ Recombinant Mouse VSIG4 Fc Chimera Protein
Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.
Marca: R&D Systems™ 4674-VS-050
411.22 EUR hasta el 2024-12-16
Use el código promocional "21630" para aplicar la oferta.
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Descripción
Measured by its ability to inhibit anti-CD3-induced proliferation of splenic T lymphocytes. Vogt, L. et al. (2006) J. Clin. Invest. 116:2817. The presence of immobilized Recombinant Mouse VSIG4 Fc Chimera inhibited the anti-CD3 response by =50%. The ED50 for this effect is 1.25-5 μg/mL.Especificaciones
NP_808457 | |
Lyophilized from a 0.2 μm filtered solution in PBS. | |
M.W. (Observed): 60-65 kDa, reducing conditions; M.W. (theoretical): 46 kDa (monomer) | |
50 μg | |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution. | |
<1.0 EU / 1 μg of the protein by the LAL method. | |
Unconjugated | |
Reconstitute at 200 μg/mL in sterile PBS. | |
VSIG4 |
Bioactivity | |
11326 | |
VSIG4 Fc Chimera | |
Mouse myeloma cell line, NS0-derived mouse VSIG4 protein Mouse VSIG4 (His20-Pro187) (N-terminus) Accession # NP_808457 IEGRMDP Mouse IgG2A (Glu98-Lys330) (C-terminus) | |
Disulfide-linked homodimer | |
Vsig4 | |
Recombinant | |
>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining. |
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