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  7. 18792594

Rotenone, Tocris Bioscience™

Catalog Number 18792594
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Cantidad:
50 mg
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Descripción

Inhibits complex I of the mitochondrial electron transport chain

Mitochondrial electron transport chain inhibitor (IC50 = 1.7 - 2.2 μM at complex I). Inhibits NADH oxidation by cardiac sarcoplasmic reticulum (IC50 = 3.4 nM). Commonly used pesticide and induces Parkinsonism in animal models. May also inhibit autophagy induction; blocks lysosomal degradation of autophagic vacuoles. Cell-permeable and brain penetrant.
Nombre del producto químico o material Rotenone
CAS 83-79-4
Fórmula molecular C23H22O6
Cantidad 50 mg
Sinónimo rotenone, dactinol, paraderil, --rotenone, tubatoxin, barbasco, --cis-rotenone, derrin, derris, cube root
Clave InChI JUVIOZPCNVVQFO-HBGVWJBISA-N
SMILES CC(=C)C1CC2=C(O1)C=CC3=C2OC4COC5=CC(=C(C=C5C4C3=O)OC)OC
Peso molecular (g/mol) 394.423
PubChem CID 6758
ChEBI CHEBI:28201
Formula Weight (peso de la fórmula) 394.42
Porcentaje de pureza >95%
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