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SLC30A8 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marca: Invitrogen PA539553
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Descripción
Slc30A8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles and is expressed at a high level in the pancreas, particularly in islets of Langerhans, and co-localizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of Slc30A8 have been identified as major genetic risk factors for the development of Type 2 diabetes, but no genetic association has been found with Type 1 diabetes. Slc30A8 expression in b-cells was found to be influenced by cytokine expression, particularly IFN-gamma and IL-1 beta.
Especificaciones
| SLC30A8 | |
| Polyclonal | |
| Unconjugated | |
| SLC30A8 | |
| ZNT8 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 169026 | |
| -20°C | |
| Liquid |
| Western Blot | |
| 1 mg/mL | |
| Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| Q8IWU4 | |
| SLC30A8 | |
| A synthetic peptide derived from the internal region of human SLC30A8 | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |