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SLC6A4 Recombinant Polyclonal Antibody (16HCLC), Invitrogen™
Rabbit Recombinant Polyclonal Antibody
Marca: Invitrogen 711108
Descripción
This antibody is predicted to react with Monkey, Horse and Cat Recombinant rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit polyclonal antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production.
SERT is an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.Especificaciones
SLC6A4 | |
Recombinant Polyclonal | |
0.5 mg/mL | |
PBS with 0.09% sodium azide; pH 7.2 | |
P31645, P31652 | |
SLC6A4 | |
Peptides corresponding to Human SLC6A4 (aa 444-462, 16-29) | |
100 μg | |
Primary | |
Human, Rat | |
Antibody | |
IgG |
Immunocytochemistry, Western Blot | |
16HCLC | |
Unconjugated | |
SLC6A4 | |
5 OCD1, 5HT transporter, 5HTT, 5-HTT, 5-HTTLPR, 5-hydroxytryptamine (serotonin) transporter, AI323329, HGNC:11050, hSERT, HTT, Na+/Cl- dependent serotonin transporter, OCD1, OTTHUMP00000163633, serotonin transporter, serotonin transporter 1, Sert, SERT1, Slc6a4, Sodium-dependent serotonin transporter, Sodium-dependent serotonin transporter (5HT transporter) (5HTT), solute carrier family 6 (neurotransmitter transporter serotonin) member 4 (5-hydroxytryptamine (serotonin) transporter), Solute carrier family 6 (neurotransmitter transporter serotonin) member 4 (5-hydroxytryptamine (serotonin) transporter), solute carrier family 6 (neurotransmitter transporter), member 4, solute carrier family 6 (neurotransmitter transporter, serotonin), member 4, solute carrier family 6 member 4, solute carrier family 6, member 4 | |
Rabbit | |
Protein A | |
RUO | |
25553, 6532 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |