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SMC1 Monoclonal Antibody (6B11), Invitrogen™
Mouse Monoclonal Antibody
Marca: Thermo Scientific MA532943
Alertas:
Para beneficiarse del descuento, los clientes deben comprar tres unidades del mismo producto al precio de catálogo en un solo pedido para recibir el 33.33% de descuento No hay límite para los múltiplos de 3 que los clientes pueden comprar PCODE:24111
Descripción
Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in various nuclear events that require structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair and global transcriptional repression. The chromo proteins are conserved in eukaryotes and lead to mitotic chromosome segregatior defects. This suggests a critical function of SMC family proteins in mitotic chromosome dynamics. SMC1 and SMC3 form a heterodimeric complex required for metaphase progression in mitotic cells. Specifically this SMC1/SMC3 complex is responsible for sister chromatid cohesion during metaphase. Mutations in the gene can lead to Cornelia de Lange syndrome 2.
Especificaciones
| SMC1 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide, pH 7.2 | |
| Q14683, Q8NDV3 | |
| SMC1A, SMC1B | |
| Synthetic peptide, corresponding to the N-terminus of Human SMC1A. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Immunohistochemistry (Paraffin), Western Blot, Western Blot | |
| 6B11 | |
| Unconjugated | |
| SMC1A | |
| 14S cohesin SMC1 subunit, 5830426I24Rik, CDLS2, chromosome segregation protein SmcB, DKFZp686L19178, DXhXs423e, DXS423E, KIAA0178, MGC138332, mitosis-specific chromosome segregation protein like protein beta, mKIAA0178, RP6-29D12.1, Sb1.8, segregation of mitotic chromosomes 1, segregation of mitotic chromosomes b, segregation of mitotic chromosomes-like 1, SM1A, SMC, SMC (segregation of mitotic chromosomes 1)-like 1, SMC protein, SMC protein 1A, SMC protein 1B, SMC1, SMC1 (structural maintenance of chromosomes 1, yeast)-like 1, SMC1 protein, SMC1 protein cohesin subunit, SMC1 structural maintenance of chromosomes 1-like 1, SMC1 structural maintenance of chromosomes 1-like 2, Smc1a, SMC-1A, smc1a.L, smc1aa, Smc1alpha, SMC-1-alpha, SMC1alpha protein, Smc1b, SMC-1B, SMC1BETA, SMC-1-beta, SMC1L1, Smc1l2, Smcb, SMC-like 1, SMC-protein, structural maintenace of chromosomes 1B, structural maintenance of chromosomes 1, structural maintenance of chromosomes 1 like 1, structural maintenance of chromosomes 1A, structural maintenance of chromosomes 1A a, structural maintenance of chromosomes 1A L homeolog, structural maintenance of chromosomes 1B, structural maintenance of chromosomes protein 1A, Structural maintenance of chromosomes protein 1B, Unknown (protein for IMAGE:8058685), XELAEV_18000030mg, xsmc1 | |
| Mouse | |
| Antigen affinity chromatography | |
| RUO | |
| 27127, 8243 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
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Título del producto
SMC1 Monoclonal Antibody (6B11), Invitrogen™ > 100 μL; Unconjugated
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