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Eurofins DiscoverX TLK2 Protein, Active
Active, N-terminal 6His-tagged, recombinant, 388-end, human TLK2, for use in Kinase Assays.
Marca: Eurofins DiscoverX 14-739
Descripción
The Tousled-like kinases, first described in Arabidopsis, are nuclear serine/threonine kinases that are potentially involved in the regulation of chromatin assembly. Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S- phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly.
GenBank BC044925
Especificaciones
mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution. | |
10 μg | |
Recombinant | |
Recombinant enzyme expressed in Sf21 insect cells | |
≥60% |
48.8 kDa | |
Human | |
N-terminal 6His | |
Truncated | |
TLK2, active |
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