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Invitrogen™ Ubinuclein 1 Monoclonal Antibody (UBN1-02)

Descripción
This antibody recognizes N-terminal part of ubinuclein 1 (UBN1), a widely expressed nuclear and adhesion complex protein. Western blotting analysis reveals UBN1 as a 165 kDa band.
Cellular senescence is a hallmark of tumor suppression and tissue aging. Senescent cells contain domains of heterochromatin, called senescence-associated heterochromatin foci (SAHF), that repress proliferation-promoting genes. The protein encoded by this gene binds to proliferation-promoting genes and is required for SAHF formation, enhancing methylation of histone H3.
Specifications
Specifications
| Antígeno | Ubinuclein 1 |
| Aplicaciones | Immunoprecipitation, Western Blot |
| Clasificación | Monoclonal |
| Clon | UBN1-02 |
| Concentración | 1 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 15mM sodium azide; pH 7.4 |
| génica | UBN1 |
| N.º de referencia del gen | Q9NPG3 |
| Alias de gen | 1110029L11Rik; 2610108L02Rik; AA673476; AW124741; HIRA-binding protein; Protein VT4; ubinuclein 1; ubinuclein-1; Ubiquitously expressed nuclear protein; Ubn1; VT; VT4 |
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