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ACVRL1 Monoclonal Antibody (OTI5C2), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Marca: Origene Technologies TA809560
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Descripción
The TGF-beta superfamily of ligands exerts its biological activity by binding to heteromeric receptor complexes two types (I and II) of the serine/threonine kinases. ALK1, like the other type I receptors, contains a cysteine rich domain with conserved cysteine spacing in the extracellular region and a glycine and serine rich domain preceding the kinase domain. The reduced human ALK1 monomer has a calculated molecular mass of approximately 37.3 kDa. Due to glycoslyation, the recombit human protein migrates as a 50-55 kDa protein in SDS-PAGE under reducing conditions. Human and mouse ALK1 share approximately 71% amino acid sequence identity in their extracellular domains. ALK1 is highly expressed in endothelial cells and other vascular tissues.Especificaciones
| ACVRL1 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| P37023 | |
| ACVRL1 | |
| Human recombit protein fragment corresponding to amino acids 22-119 of human ACVRL1 produced in E.coli. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Western Blot | |
| OTI5C2 | |
| Unconjugated | |
| ACVRL1 | |
| ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 94 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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Título del producto
ACVRL1 Monoclonal Antibody (OTI5C2), TrueMAB™, OriGene
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