Banoxantrone dihydrochloride

Prodrug topoisomerase II inhibitor

Brand: Tocris Bioscience 4219/5

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Product Code. 18706416

127.00€ / 5 miligramos

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Description

Banoxantrone dihydrochloride is a bioreductive prodrug; activated by hypoxia to yield the topoisomerase II inhibitor AQ4. Displays little to no cytotoxic activity against 60 tumor cell lines tested under oxic conditions (IC50 >100 μM). Exhibits anti-tumor efficacy in vivo when combined with oxic cell cytotoxins; enhances the anti-tumor effect of cyclophosphamide (Cat. No. 4091) in a mouse tumor model.

Specifications

Nombre del producto químico o material	1,4-Bis[[2-(dimethyloxidoamino)ethyl]amino]-5,8-dihydroxy-9,10-anthracenedione dihydrochloride
Intervalo de porcentaje de ensayo	>98%
Fórmula molecular	C₂₂H₂₈N₄O₆.2HCl

CAS	252979-56-9
Cantidad	5 mg
Formula Weight (peso de la fórmula)	Observed MW: 517.4

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Banoxantrone dihydrochloride

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