missing translation for 'onlineSavingsMsg'
Learn More
Learn More
STEMCELL Technologies BIO
WNT pathway activator; Inhibits GSK3
Marca: STEMCELL Technologies 72032
Detalles adicionales : Peso : 0.01000kg
Descripción
- BIO is an indirubin compound that is cell-permeable and is a selective and potent reversible inhibitor of GSK3α and GSK3β (IC50 = 5 nM) and functions as a WNT activator
- Enhances reprogramming of mouse fibroblasts, neural stem cells, and thymocytes to induced pluripotent stem (iPS) cells (Lluis et al.)
- Maintains self-renewal of mouse embryonic stem (ES) cells in the absence of LIF (Sato et al.)
- Maintains self-renewal of human ES cells in unconditioned medium through a SMAD 2/3 dependent mechanism (James et al.), Sato et al.)
- Induces proliferation of neonatal and adult rat cardiomyocytes (Tseng et al.)
- Promotes differentiation of cardiomyocytes from human ES and iPS cells (Lian et al.)
Especificaciones
| 667463-62-9 | |
| 1 mg | |
| ≥98% |
| GSK 3 IX; MLS 2052; 6-Bromoindirubin-3'-oxime | |
| C16H10BrN3O2 |