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Eurofins DiscoverX DMPK Protein, Active
Active, 6His-tagged, recombinant, human DMPK, amino acids 1-549, for use in Kinase Assays.
Marca: Eurofins DiscoverX 14-649
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Descripción
Myotonic dystrophy (DM1) is the most common form of muscular dystrophy in adults, caused by amplification of an unstable (CTG)n repeat in the 3' untranslated region (3'-UTR) of the DM1 protein kinase (DMPK) gene. Myotonic dystrophy protein kinase (DMPK) is a serine threonine kinase encoded by the DM-1 locus.
GenBank NM_004409
Especificaciones
| mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution. | |
| 10 μg | |
| Recombinant | |
| Recombinant enzyme expressed in Sf21 insect cells | |
| ≥66% |
| 65 kDa | |
| Human | |
| N-terminal 6His | |
| Truncated | |
| DMPK, active |