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Gibco™ Human R-Spondin 1 Recombinant Protein, PeproTech®
Recombinant Protein
Marca: Gibco™ 120-38-100UG
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Descripción
120-38-1MG will be provided as 2 x 500 μg (120-38-500UG). Recombinant Human R-Spondin-1 is a 26.7 kDa protein consisting of 243 amino acid residues. Due to glycosylation, R-Spondin-1 migrates at an apparent molecular weight of approximately 40.0 kDa by SDS-PAGE analysis under reducing conditions. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
This gene is a member of the R-spondin family and encodes a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects.
Especificaciones
| Q2MKA7 | |
| protein with no preservative | |
| 26.7 kDa | |
| 100 μg | |
| RUO | |
| CRISTIN3; cristin-3; cysteine-rich and single thrombospondin domain-containing protein 3; FLJ40906; hRspo1; mCristin-3; RGD1565558; Roof plate-specific spondin-1; RP11-566C13.1; RSPO; RSPO1; Rspondin; R-spondin; R-spondin 1; R-spondin homolog; R-spondin homolog (Xenopus laevis); R-spondin-1; thrombospondin type 1 domain containing gene Rspondin | |
| RSPO1 | |
| Unconjugated | |
| SRGIKGKRQR RISAEGSQAC AKGCELCSEV NGCLKCSPKL FILLERNDIR QVGVCLPSCP PGYFDARNPD MNKCIKCKIE HCEACFSHNF CTKCKEGLYL HKGRCYPACP EGSSAANGTM ECSSPAQCEM SEWSPWGPCS KKQQLCGFRR GSEERTRRVL HAPVGDHAAC SDTKETRRCT VRRVPCPEGQ KRRKGGQGRR ENANRNLARK ESKEAGAGSR RRKGQQQQQQ QGTVGPLTSA GPA | |
| CHO cells | |
| ≥ 95% by SDS-PAGE gel and HPLC analyses. |
| Functional Assay | |
| 284654 | |
| Human R-Spondin 1 | |
| CHO cells | |
| <1 EU/ μg | |
| RSPO1 | |
| R-Spondin-1 enhances BMP-2-mediated differentiation of MC3T3-E1 cells. The expected ED50 is 1.0-3.0 ug/ml | |
| Recombinant | |
| -20°C | |
| Lyophilized |
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Título del producto
Gibco™ Human R-Spondin 1 Recombinant Protein, PeproTech® > 100 μg; Unlabeled
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