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ACROBiosystems Influenza A [A/Shanghai/2/2013(H7N9)] Hemagglutinin (HA) Protein, Fc Tag
Marca: ACROBiosystems HA9-V5253-100UG
Detalles adicionales : Peso : 0.00001kg
Descripción
Influenza, commonly known as “the flu”, is an infectious disease of birds and mammals caused by RNA viruses of the family Orthomyxoviridae, the influenza viruses. The virus is divided into three main types (Influenzavirus A, Influenzavirus B, and Influenzavirus C), which are distinguished by differences in two major internal proteins (hemagglutinin (HA) and neuraminidase (NA), which are the most important targets for the immune system. The type A viruses are the most virulent human pathogens among the three influenza types and cause the most severe disease. The serotypes that have been confirmed in humans, ordered by the number of known human pandemic deaths, are: H1N1, H2N2, H3N2, H5N1, H7N7, H1N2, H9N2, H7N2, H7N3, H10N7, H7N9. H7N9 is a serotype of the species Influenzavirus A (avian influenza virus or bird flu virus). H7 normally circulates amongst avian populations with some variants known to occasionally infect humans. An H7N9 virus was first reported to have infected humans in 2013 in China.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 82.5 kDa. The protein migrates as 100-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Especificaciones
AHF20558.1 | |
100 μg | |
Asp 19 - Gly 338, Leu 341 - Asp 523 | |
HA,Hemagglutinin | |
Unconjugated | |
Fc Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |
82.5 kDa | |
Influenza A [A/Shanghai/2/2013(H7N9)] HA, Fc Tag (HA9-V5253) is expressed from human 293 cells (HEK293). It contains AA Asp 19 - Gly 338, Leu 341 - Asp 523 (Accession # R4NN21-1). | |
-20°C | |
Hemagglutinin (HA) | |
Influenza | |
50 mM Tris, 100 mM Glycine, pH7.5 | |
HEK293 | |
Viral Proteins |