STEMCELL Technologies IWR-1-endo

WNT pathway inhibitor; AXIN2 stabilizer

Marca: STEMCELL Technologies 72562

Detalles adicionales : Peso : 0.05000kg

Código de producto. 17100092

Fecha estimada de envío: 31-07-2024
para ver el stock

Descripción

IWR-1-endo potently inhibits WNT signaling by blocking a cell-based WNT/β-catenin pathway reporter response with an IC₅₀ value of 180 nM (Chen et al.) It inhibits WNT-induced accumulation of β-catenin, through stabilization of the destruction complex member AXIN2 (Chen et al.)
Promotes self-renewal and maintains pluripotency of human embryonic stem cells and mouse Epi-stem cells when used in combination with CHIR99021 (Kim et al.) DIFFERENTIATION
Promotes differentiation of cardiomyocytes from human pluripotent stem cells (PSCs) that have been induced to mesoderm by addition of Activin A and/or BMP4 (Ren et al.; Willems et al.)
Induces the differentiation of human PSC-derived alveolar epithelial type II (AETII) to AETI cells (Ghaedi et al.)

Especificaciones

Sugerencias de productos

Descripción