JNK Mouse anti-Human, Mouse, Rat, Clone: 1A12E1, Proteintech

Descripción

This protein can be phosphorylated and this antibody recognizes the 46 kDa and 55 kDa bands in western blot.

C-Jun N-terminal Kinase (JNK) is also known as Mitogen-activated protein kinase (MAPK8). It belongs to the MAPK superfamily of stress-activated protein kinases. MAPKs are Serine-threonine protein kinases that are activated in response to a variety of extracellular stimuli, and mediate signal transduction from the cell surface to the nucleus. JNK is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. JNK pathways are activated by stress and inflammatory signals. JNK is expressed as ten different isoforms due to differential mRNA splicing. The predomit forms are JNK1 and JNK2.