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STEMCELL Technologies R848
Immune modulator; Inhibits TLR7 and TLR8
Marca: STEMCELL Technologies 73782
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Descripción
- R848 is an imidazoquinoline and agonist of Toll-like receptors (TLRs) 7 and 8
- It mimics the pathogen-associated molecular patterns that activate immune cells through TLR7 and TLR8, and thereby acts as an immune-response modifier
- It demonstrates potent anti-tumor and anti-viral properties (IC50 = 4.2 μM; Seganish et al.) which appear to be mediated predominantly through the induction of cytokines, including interferon (IFN)-α and interleukin (IL)-12 due to stimulation of monocytes, macrophages, and dendritic cells (Bernstein et al.; Hattermann et al.; Nian et al.)
Especificaciones
144875-48-9 | |
10 mg | |
≥98% |
Resiquimod; S 28463 | |
C17H22N4O2 |