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Tocris Bioscience™ SGC 6870
Potent and selective PRMT6 allosteric inhibitor
Marca: Tocris Bioscience™ 7182/5
Detalles adicionales : Peso : 0.00970kg
Descripción
SGC 6870 is a potent and selective protein arginine methyltransferase 6 (PRMT6) allosteric inhibitor (IC50 = 77 nM). Exhibits selectivity over all other PRMTs and 23 methyltransferases. In HEK293T cells overexpressing PRMT6, inhibits asymmetric dimethylation of H3R2 (IC50 = 0.8 μM) Negative control SGC 6870N (Cat. No. 7184) also available.Especificaciones
| (R)-4-(5-Bromothiophene-2-carbonyl)-5-(3,5-dimethylphenyl)-7-methyl-1,3,4,5-tetrahydro-2H-benzo[e][1,4]diazepin-2-one | |
| 5 mg | |
| C23H21BrN2O2S |
| 2561471-27-8 | |
| Protein Arginine Methyltransferase Inhibitors | |
| 0.98 |