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Ku70/Ku80 Monoclonal Antibody (162), Invitrogen™
Mouse Monoclonal Antibody
Marca: Invitrogen MA512938
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Descripción
MA5-12938 targets Ku (p70/p80) in FACS, GS, ICC/IF, and IHC (P) applications and shows reactivity with Human, Non-human primate, Mouse and Xenopus laevis samples. This antibody does not cross-react with mouse in immunofluorescent applications, but does react with mouse in FACS applications. The MA5-12938 immunogen is human B cell nuclei from plasmacytoid 2p68 cells.
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008].
Especificaciones
| Ku70/Ku80 | |
| Monoclonal | |
| 0.2 mg/mL | |
| PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4 | |
| P12956, P13010, P23475, P27641 | |
| XRCC5, xrcc5.L, XRCC6, xrcc6.L | |
| Human B cell nuclei from plasmacytoid 2p68 cells | |
| 500 μL | |
| Primary | |
| Human, Mouse, Non-human Primate, X. laevis | |
| Liquid |
| Flow Cytometry, Gel Shift, Immunocytochemistry, Immunohistochemistry (Paraffin) | |
| 162 | |
| Unconjugated | |
| XRCC5 | |
| 5'-deoxyribose-5-phosphate lyase Ku70; 5'-dRP lyase Ku70; 5'-dRP/AP lyase Ku70; 70 kDa subunit of Ku antigen; 70kDa; 86 kDa subunit of Ku antigen; AI314015; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase 2 subunit 2; ATP-dependent DNA helicase II 70 kDa subunit; ATP-dependent DNA helicase II 80 kDa subunit; ATP-dependent DNA helicase II, 70 kDa subunit; CTC box binding factor 75 kDa subunit; CTC box-binding factor 75 kDa subunit; CTC box-binding factor 85 kDa subunit; CTC75; CTC85; CTCBF; DNA repair protein XRCC5; DNA repair protein XRCC6; G22P1; G22P2; KARP1; KARP-1; Ku autoantigen p70 subunit; ku autoantigen protein p70 homolog; Ku autoantigen protein p86 homolog; Ku autoantigen, 70kDa; Ku autoantigen, 80kD); Ku autoantigen, 80kDa; Ku p70; Ku p80; KU70; Ku70 DNA-binding component of DNA-dependent proteinkinase complex (thyroid autoantigen 70 kDa); KU80; Ku86; Ku86 autoantigen related protein 1; KUB2; Kup70; Kup80; lupus Ku autoantigen protein p70; Lupus Ku autoantigen protein p86; ML8; NFIV; Nuclear factor IV; thyroid autoantigen; thyroid autoantigen 70 kDa; thyroid autoantigen 70kD (Ku antigen); thyroid autoantigen 70kDa (Ku antigen); thyroid-lupus autoantigen; thyroid-lupus autoantigen p70; TLAA; XELAEV_18023498mg; XELAEV_18044412mg; X-ray repair complementing defective repair in Chinese hamster cells 5; X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining); X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kDa); X-ray repair complementing defective repair in Chinese hamster cells 5 L homeolog; X-ray repair complementing defective repair in Chinese hamster cells 6; X-ray repair complementing defective repair in Chinese hamster cells 6 L homeolog; X-ray repair cross complementation (double-strand-break rejoining; X-ray repair cross complementation (double-strand-break rejoining; Ku autoantigen, 80kD); X-ray repair cross complementing 5; X-ray repair cross complementing 6; X-ray repair cross-complementing protein 5; X-ray repair cross-complementing protein 6; xrcc5; xrcc5.L; xrcc5-a; Xrcc6; xrcc6.L | |
| Mouse | |
| Ammonium sulfate precipitation | |
| RUO | |
| 14375, 22596, 2547, 394397, 398357, 7520 | |
| 4° C | |
| IgG2a |
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Título del producto
Ku70/Ku80 Monoclonal Antibody (162), Invitrogen™ > 500 μL; Unconjugated
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