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TACC3 Monoclonal Antibody (OTI6C6), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Marca: Origene Technologies TA501262
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Descripción
TACC1 is located on 8p11 chromosomal region that is amplified in approximately 15% of all breast tumor samples. The short arm of chromosome 8 also contains FGFR1 whose expression is enhanced in most breast cancer tumors. TACC family members, TACC1, TACC2, and TACC3, map very closely to the corresponding FGFR1, FGFR2, FGFR3 genes on chromosomes 4,8, and 10. Subsequently, since they are phylogenetically related, it is proposed that TACC and FGFR have similar roles in cell growth and differentiation. Also, TACC1 contains a conserved C-terminal region as in the Drosophila homolog, D-TACC. It has been shown that D-TACC is necessary for normal spindle function, and the mammalian TACC proteins appears to interact with centrosomes and microtubules in a similar manner.Especificaciones
| TACC3 | |
| Monoclonal | |
| 0.53 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| Q9Y6A5 | |
| TACC3 | |
| Full length human recombit protein of human TACC3 produced in HEK293T cell. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot | |
| OTI6C6 | |
| Unconjugated | |
| TACC3 | |
| ERIC-1, ERIC1 | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 10460 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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Título del producto
TACC3 Monoclonal Antibody (OTI6C6), TrueMAB™, OriGene
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