Ethinylestradiol Polyclonal Antibody, Invitrogen™

Descripción

PA1-75138 specifically detects Ethinylestradiol. PA1-75138 has been successfully used in ELISA applications. The PA1-75138 immunogen is Ethinylestradiol(3)-BTG.

Ethinyl Estradiol is a semisynthetic alkylated estradiol with a 17-alpha-ethinyl substitution. It has high estrogenic potency when administered orally, and is often used as the estrogenic component in oral contraceptives. Ethinyl estradiol binds to the estrogen receptor complex and enters the nucleus, activating DNA transcription of genes involved in estrogenic cellular responses. This agent also inhibits 5-alpha reductase in epididymal tissue, which lowers testosterone levels and may delay progression of prostatic cancer. In addition to its antineoplastic effects, ethinyl estradiol protects against osteoporosis. In animal models, short-term therapy with this agent has been shown to provide long-term protection against breast cancer, mimicking the antitumor effects of pregnancy. [National Center for Biotechnology Information. PubChem Compound Database; CID=5991].